When does brain aging accelerate? Dangers of quadratic fits in cross-sectional studies
نویسندگان
چکیده
منابع مشابه
When does brain aging accelerate? Dangers of quadratic fits in cross-sectional studies
Many brain structures show a complex, non-linear pattern of maturation and age-related change. Often, quadratic models (beta(0) + beta(1)age + beta(2)age(2) + epsilon) are used to describe such relationships. Here, we demonstrate that the fitting of quadratic models is substantially affected by seemingly irrelevant factors, such as the age-range sampled. Hippocampal volume was measured in 434 h...
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ژورنال
عنوان ژورنال: NeuroImage
سال: 2010
ISSN: 1053-8119
DOI: 10.1016/j.neuroimage.2010.01.061